Mathematical Medicine LLC is a research organization specializing in statistical methodology and large-scale data curation projects, with a particular emphasis on statistical genetics and genetic data.

Who We Are

Veronica Vieland, PhD

Executive Director

Dr. Veronica Vieland is the founder and Executive Director of Mathematical Medicine LLC. Throughout her academic career, Dr. Vieland’s research has focused on the measurement of statistical evidence, both from a theoretical perspective and also as the foundation for understanding human genetic and genomic data. On the genetics side, she focuses on developing statistical methods for discovering the genetic architecture of complex clinical phenotypes. She has led development of a novel class of statistical genetic techniques, implemented in the computer package Kelvin, and used Kelvin to study the genetics of numerous clinical conditions, including autism, schizophrenia, bipolar disorder, cleft lip and palate, autoimmune thyroid disease, papillary thyroid cancer and genetic modifiers in Duchenne muscular dystrophy. The other arm of this work has been the development of the high-performance computational approaches required to utilize the methods. On the theoretical side, she is developing an absolute scale for the measurement of statistical evidence, following the template of the absolute scale for measurement of temperature.

Dr. Vieland received her undergraduate degree in Philosophy from Barnard College and graduate degrees in Philosophy (Mathematical Logic and Philosophy of Science) and Biostatistics from Columbia University, where she also completed a Postdoctoral Fellowship in the Department of Child Psychiatry. Subsequent to completing her training, she was an academic for over 30 years, most recently serving as the Battelle Endowed Chair in Computational Biology at The Abigail Wexner Research Institute at Nationwide Children’s Hospital, where she also served as Vice President for Computational Research and as the Director of the Battelle Center for Mathematical Medicine, and as Professor in the Departments of Pediatrics and Statistics at The Ohio State University, where she remains Professor Emerita. She has published over 150 papers and presented her work at numerous national and international venues. She has been the recipient of two NIH Career Development Awards, and she is an elected fellow of the American Psychopathological Association (APPA) and the American Association for the Advancement of Science (AAAS).

William Valentine-Cooper

Senior Systems Developer

William has a bachelor’s degree in Computer and Information Science from The Ohio State University, and has worked for over 40 years as a systems architect, developer and project leader in many different industries, especially telecommunications. He has extensive experience with a wide variety of operating systems, languages, databases and tools, and has developed software ranging from high-performance device drivers to accounting systems and cellular network alarm management systems. He has worked with Dr. Vieland since 2007. He is developing software and databases for MathMed research projects, managing application performance, and providing general technical support as required.

Jo Valentine-Cooper

Applications Developer

Jo is a “second-generation computer scientist”, formally educated at Bowling Green State University. She has over 25 years of experience with systems administration, website programming, applications development, and user technical support using many different computing environments, and has worked with Dr. Vieland since early 2013. At MathMed, she’s employed in applications development, testing, documentation, quality control, and IT support.


John Burian, MS

Senior Systems Developer

John received his MS in Computer Science from Bowling Green State University in 1992, and has worked with Dr. Vieland since 2007. In his work for MathMed, John develops parallel computation systems for genetic analysis, implements pipelines for data analyses on clinical research projects, and provides supplemental system administration. He also continues to work with Dr. Vieland on various university-based research grants.

Sang-Cheol Seok, PhD

Systems Programmer

Sang-Cheol received his BS and MS degrees in Mathematics at the Pusan National University, Pusan, Korea and a PhD in Computer Science at the University of Iowa. He has expertise in Data mining, High Performance Computing, Numerical Analysis and Combinatorial Scientific Computing. He has worked with Dr. Vieland since 2007, acquiring specialized expertise in the underlying likelihood calculations used by Kelvin, and developing Kelvin’s unique multidimensional numerical integration algorithm. In his work for MathMed, he works with Dr. Vieland on the development and application of evidence measurement scales for biomedical research. He also continues to work with Dr. Vieland on university-based research grants.

Susan Valentine-Cooper

Business Manager

Susan has a BS in MIS and Accounting from The Ohio State University and 40 years of income tax preparation experience. While a programmer/tax specialist with CompuServe, she helped develop HR Block’s original conversion to computer-based tax prep. She has extensive experience with accounting and tax compliance for small businesses, estates, and non-profits. Having been a Senior Project Manager, Executive Director for a synagogue, and entrepreneur, she has wide knowledge of budgeting, bookkeeping, business workflows, and government compliance, which she applies as the business manager for Mathematical Medicine LLC.

Our Projects

(Coming Soon)

Our Software

We'll have downloads for all our software available shortly.